What is Aortic Stenosis?
The aortic valve is located between the left ventricle and the aorta. It functions as a one-way valve allowing oxygen rich blood to flow out of the left ventricle to the rest of the body, then closes to prevent any blood from flowing back into the left ventricle. Aortic stenosis refers to the narrowing or obstruction of blood flow through the valve. There are three types of aortic stenosis. Subvalvar aortic stenosis refers to a narrowing or obstruction below the valve. Valvar aortic stenosis refers to a narrowing or obstruction at the valve. Supravalvar aortic stenosis refers to a narrowing or obstruction above the valve. The most common cause of aortic stenosis is a bicuspid aortic valve. Normally, the aortic valve has three leaflets (or cusps) that open to allow blood to pass through. Some people are born with only 2 cusps (bicuspid valve). These valves do not open well and over time may get more narrow. When the valves do not open well or there is an obstruction, the heart has to work harder to move blood out of the heart to the body.
How do we diagnose Aortic Stenosis?
Aortic Stenosis is usually diagnosed after a referral for a murmur. A murmur is a sound that the physician can hear when listening with a stethoscope. The sound is caused by the turbulence of the blood as it is pushed through the narrowing. If the valve is bicuspid, the physician may also hear a sound called a "click" which is caused by the valve opening. An echocardiogram can be done to confirm the diagnosis and determine the amount of narrowing. Mild stenosis usually has no symptoms, but will require regular monitoring to assess for any increased stenosis. Intervention will be needed for severe stenosis. At this point the heart is having to work harder and may not be able to pump enough blood to meet the needs of the body, especially during exercise.
How do we treat Aortic Stenosis?
Usually the first line of treatment is a heart catheterization and attempt at opening the valve, typically with a balloon. This is usually not permanent and surgery is needed at a later point. Surgical intervention involves opening the valve or replacing it with a mechanical valve which will usually require the use of chronic medicines to thin the blood. Another procedure called the "Ross procedure" involves replacing the aortic valve with the patient's own pulmonary valve. The pulmonary valve is then usually replaced with a homograft, which is a valve from a human, or occasionally with a cow valve.
© 2014 Monroe Carell Jr. Children's Hospital at Vanderbilt