Monroe Carell Jr. Children's Hospital at Vanderbilt
Monroe Carell Jr. Children's Hospital at Vanderbilt
Monroe Carell Jr. Children's Hospital at Vanderbilt
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Monroe Carell Jr.
Children's Hospital
at Vanderbilt
2200 Children's Way
Nashville, TN 37232

(615) 936-1000

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Type 1 Diabetes TrialNet

(888) 884-8638

If your child is a family member of someone with type-1 diabetes, there’s a greater risk he or she could develop this disease. Children’s Hospital wants you to know about a free screening program that could help identify this risk and help you take positive steps toward improving your child’s health.

Type 1 Diabetes TrialNet

Type 1 Diabetes TrialNet is a network of major research centers. Its goal is to find the causes of type-1 diabetes, and to work toward prevention and early treatment of this disease.

The TrialNet research network selected Vanderbilt University Medical Center as a Major Affiliate in May 2006. In October 2009, Vanderbilt received designation as a TrialNet Clinical Center. By working together with other research centers around the world, there is hope for improving the lives of those with type-1 diabetes much more quickly.

TrialNet receives funding from the National Institutes of Health, the Juvenile Diabetes Research Foundation, and the American Diabetes Association.

How TrialNet works

TrialNet’s worldwide network of health care providers offers free screening for family members of persons who have been diagnosed with type-1 diabetes. These free screenings take place throughout the U.S. at locations convenient to you.

TrialNet’s screenings create no medical records on individuals screened. There are also no medical bills involved.

There are three goals TrialNet hopes to achieve through these screenings.

  1. Find persons at higher risk for developing type-1 diabetes.
  2. Find persons who may be a good fit for TrialNet studies on preventing or delaying the onset of this disease.
  3. Learn more about what happens in the body of a person in the months and years prior to the disease’s development.

More about type-1 diabetes

In type-1 diabetes, a person’s immune system attack and destroy the cells that produce insulin, a substance the body uses to transport glucose to cells as a food source.

As with other immune system reactions, the body creates antibodies to make this process more efficient. When the immune system attacks a person’s own cells rather than viruses or bacteria, it produces autoantibodies.

TrialNet’s screening processes can detect the presence of autoantibodies years before type-1 diabetes would be diagnosed. With this information, you and your health care provider could be better prepared for the disease’s onset. Identifying your child as likely to develop type-1 diabetes may also make your family eligible for further studies as TrialNet works toward preventive measures and cures.

How to know if you’re right for the TrialNet study

TrialNet is seeking children and adults for this study. Eligibility is open to persons who have a close blood relative who has been diagnosed with type-1 diabetes, especially those diagnosed under age 40 and who began using insulin within one year.

TrialNet may be interested in screening you or your child if

  1. Either of you are between the ages of 1 and 45 and have a sibling, child, or parent with type-1 diabetes.
  2. Either of you are between the ages of 1 and 20, and have a niece, nephew, aunt, uncle, grandparent, cousin or half-sibling with type-1 diabetes.

You or your child may not be eligible for this study if

  1. You take medicine to lower your blood glucose.
  2. You take medicine that affects your immune system.
  3. You are taking steroidal medications, possibly including asthma inhalers.

How to register for TrialNet

Call 615-936-TNET or 888-VU4-TNET, or email to arrange phone consent and assent for participation. Print one Screening Form and one Family History Form for each person volunteering (see below). Print the Adult Consent form for volunteers 18 and over. Print the Parent Consent for parents and legally authorized representatives to give permission for a child to participate. Children also need to give their assent on the appropriate form below.

After giving phone consent and completing the paperwork, please fax the consents and assents along with one screening form and one family history form per volunteer to our secure fax line, 615-936-7001. We will mail you a lab kit to the address listed on the Screening Form.

You can take the lab kit to a lab or medical professional in your area to complete the blood draw.

Ship the lab kit back to us in the FedEx pak that we will provide you. Lab and shipping costs are covered by our research grant.

What happens at a TrialNet screening

Health care providers taking part in TrialNet screening procedures require a small amount of blood, about a tablespoon, from eligible children and adults. These blood draws can be done at TrialNet sites, or by TrialNet staff at diabetes camps and walks, or other similar events.

If you prefer, TrialNet can also send you a screening kit you can take to your family doctor or local lab. The kit includes instructions on returning it to TrialNet. Once returned, TrialNet screens blood samples for three different kinds of autoantibodies. Results become available within four to six weeks.

Contact TrialNet
(888) 884-8638

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Last Edited: November 13, 2017
Valued Participant of Vanderbilt Health Affiliated Network